
単一分子レベルでの完全長タンパク質の配列決定と特性解析を可能にする新しい手法の開発


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A technique for threading long protein strands through a nanopore by electrophoresis and back using a protein unfoldase motor, ClpX, enables single protein molecules to be analyzed multiple times with single-amino-acid sensitivity.

Multi-pass, single-molecule nanopore reading of long protein strands - Nature

長いタンパク質鎖の単一分子ナノポア読み取りにおける多重パス