
베타 진동은 전두엽, 대상회, 기저핵 등을 포함하는 전체 뇌 네트워크에서 발생하며, 이 네트워크는 도파민 신호와 유의미한 상관관계를 보인다.


coremsg

Brain rhythms can facilitate neural communication for the maintenance of brain function. Beta rhythms (13–35 Hz) have been proposed to serve multiple domains of human ability, including motor control, cognition, memory and emotion, but the overarching organisational principles remain unknown. To uncover the circuit architecture of beta oscillations, we leverage normative brain data, analysing over 30 hours of invasive brain signals from 1772 cortical areas in epilepsy patients, to demonstrate that beta is the most distributed cortical brain rhythm. Next, we identify a shared brain network from beta dominant areas with deeper brain structures, like the basal ganglia, by mapping parametrised oscillatory peaks to whole-brain functional and structural MRI connectomes. Finally, we show that these networks share significant overlap with dopamine uptake as indicated by positron emission tomography. Our study suggests that beta oscillations emerge in cortico-subcortical brain networks that are modulated by dopamine. It provides the foundation for a unifying circuit-based conceptualisation of the functional role of beta activity beyond the motor domain and may inspire an extended investigation of beta activity as a feedback signal for closed-loop neurotherapies for dopaminergic disorders.

### Competing Interest Statement

WJN received honoraria for consulting from InBrain : Neuroelectronics that is a neurotechnology company and honoraria for talks from Medtronic that is a manufacturer of deep brain stimulation devices unrelated to this manuscript.

Cortical beta oscillations map to shared brain networks modulated by dopamine

침습적-뇌-신호-분석과-mri-연결성-매핑을-통해-도파민에-의해-조절되는-공유-뇌-네트워크에-매핑된-베타-진동


침습적 뇌 신호 분석과 MRI 연결성 매핑을 통해 도파민에 의해 조절되는 공유 뇌 네트워크에 매핑된 베타 진동
