
IL-23에 의해 유도되는 CTLA-4 발현 ILC3가 장내 염증을 억제하는 핵심적인 조절 경로이다.


coremsg

Subsets of ILC3s upregulate the immunoregulatory checkpoint molecule CTLA-4 after stimulation in a microbiota-dependent manner, and advances to support CTLA-4+ ILC3s may represent a treatment opportunity in IL-23-driven chronic inflammation.

CTLA-4-expressing ILC3s restrain interleukin-23-mediated inflammation - Nature

il-23에-의해-유도되는-ctla-4-발현-ilc3가-염증을-억제하는-메커니즘


IL-23에 의해 유도되는 CTLA-4 발현 ILC3가 염증을 억제하는 메커니즘
