
Multitarget stool-based tests, including DNA, RNA, and protein-based approaches, demonstrate improved sensitivity for detecting colorectal cancer and advanced precancerous lesions compared to the current standard fecal immunochemical test (FIT), but may also have lower specificity leading to more false-positive results.


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Several new multitarget stool-based screening tests on the horizon may improve early colorectal cancer detection, according to findings from recent analyses.

What to Know About the Next-Gen FIT for CRC Screening

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Next-Generation Stool-Based Tests Show Promise for Improved Colorectal Cancer Screening
