CAR-T cell therapies may be directly linked to the development of secondary tumors, particularly those originating from T lymphocytes, according to the European Medicines Agency.
폐암 치료에 있어 항체-약물 접합체(ADC), EGFR 돌연변이, ALK 융합 등 다양한 표적 치료법이 발전하고 있으며, 이를 통해 환자의 생존율 향상과 부작용 감소를 기대할 수 있다.
肺がんの標的療法分野で、抗体薬物複合体(ADC)、EGFR変異、ALK融合遺伝子変異などの新しい治療アプローチが注目されている。これらの治療法は患者の予後を大きく改善する可能性がある。
Significant progress has been made in the development and application of targeted therapies, including antibody-drug conjugates (ADCs) and bispecific antibodies, for the treatment of lung cancer, offering new hope for improved patient outcomes.
The evolutionary path to acquired resistance to androgen receptor signaling inhibition (ARSI) in prostate cancer is dependent on the timing of treatment. In established tumors, resistance occurs through polyclonal adaptation of drug-sensitive clones, while in minimal residual disease, resistance occurs through outgrowth of pre-existing resistant clones.
Black individuals have a significantly higher incidence of dermatofibrosarcoma protuberans (DFSP), a rare cutaneous soft tissue sarcoma, compared to White individuals. Older age and larger tumor size are associated with poorer overall survival and cancer-specific survival for DFSP patients.
胃食道接合部腺癌の診断と治療において、バイオマーカーの評価、手術前後の治療戦略、再発時の治療アプローチなど、最新の知見が示されている。
Optimizing the management of gastroesophageal junction adenocarcinoma through comprehensive biomarker testing, personalized treatment strategies, and innovative therapeutic approaches.
胃食道接合部腺癌および食道腺癌の治療において、免疫療法の導入や新しい分子標的薬の開発により、治療成績の向上が期待されている。
Experts discuss the evolving landscape of second-line and later-line therapies for gastroesophageal junction and esophageal adenocarcinoma, including the impact of frontline immunotherapy, management of specific molecular subtypes, and emerging targeted agents.