
중뇌 도파민 활성화는 실험 조건에 따라 다양한 동적 변화를 보이며, 이는 보상 예측 오류 신호로서의 도파민 기능을 이해하는 데 중요한 제약 조건을 제공한다.


coremsg

Mesolimbic dopamine activity occasionally exhibits ramping dynamics, reigniting debate on theories of dopamine signaling. This debate is ongoing partly because the experimental conditions under which dopamine ramps emerge remain poorly understood. Here, we show that during Pavlovian and instrumental conditioning, mesolimbic dopamine ramps are only observed when the inter-trial interval is short relative to the trial period. These results constrain theories of dopamine signaling and identify a critical variable determining the emergence of dopamine ramps.

### Competing Interest Statement

The authors have declared no competing interest.

Mesolimbic dopamine ramps reflect environmental timescales

보상-예측-오류-신호로서의-중뇌-도파민-활성화-동적-변화


보상 예측 오류 신호로서의 중뇌 도파민 활성화 동적 변화
