
생쥐 집단의 공간 점유 패턴을 통해 개별 선호도와 사회적 상호작용을 구분하여 정량화할 수 있으며, 전두엽 피질의 신경 가소성 저하가 이러한 사회적 상호작용에 미치는 영향을 확인할 수 있다.


coremsg

Social interactions are a crucial aspect of behavior in mice. Nonetheless, it is often difficult to distinguish the effects of interactions, from independent animal behavior. Distinguishing interactions from individual preferences is important to describe how information is transmitted in a horde and to predict behavioral patterns of a whole group. We combine high-throughput data collected in mice housed and location-tracked over multiple days in an ecologically-relevant environment (Eco-HAB system) with statistical inference models to learn the rules controlling the collective dynamics of groups of 10 to 15 individuals. We reproduce the distribution for the co-localization patterns, show they are stable over time, and find that the distribution of the inferred interaction strength captures the social structure among the animals. By separating interactions from individual preferences, we show that affecting neuronal plasticity in the prelimbic cortex - a brain structure crucial for processing social information and interacting with others - does not eliminate social interactions, yet make it harder to transmit information between mice.

### Competing Interest Statement

The authors have declared no competing interest.

Modelling collective behavior in groups of mice housed under semi-naturalistic conditions

생태학적-환경에서-사육된-생쥐-집단의-집단-행동-모델링


생태학적 환경에서 사육된 생쥐 집단의 집단 행동 모델링
