
유연한 의사결정 과정에서 감각 평가와 행동 선택이라는 서로 다른 신경 과정 간의 복잡한 상호작용이 선택성 특화 피드백 연결에 의해 매개된다.


coremsg

Neural activity in the primate brain correlates with both sensory evaluation and action selection aspects of decision-making. However, the intricate interaction between these distinct neural processes and their impact on decision behaviors remains unexplored. Here, we examined the interplay of these decision processes in posterior parietal cortex (PPC) when monkeys performed a flexible decision task. We found that the PPC activity related to monkeys’ abstract decisions about visual stimuli was nonlinearly modulated by monkeys’ following saccade choices directing outside each neuron’s response field. Recurrent neural network modeling indicated that the feedback connections, matching the learned stimuli-response associations during the task, mediated such feedback modulation. Further analysis on network dynamics revealed that selectivity-specific feedback connectivity intensified the attractor basins of population activity underlying saccade choices, thereby increasing the consistency of flexible decisions. These results highlight an iterative computation between different decision processes, mediated primarily by precise feedback connectivity, contributing to the optimization of flexible decision-making.

### Competing Interest Statement

The authors have declared no competing interest.

Nonlinear feedback modulation contributes to the optimization of flexible decision-making

유연한-의사결정-과정에서-선택성-특화-피드백-연결이-서로-다른-신경-과정의-상호작용을-매개한다


유연한 의사결정 과정에서 선택성 특화 피드백 연결이 서로 다른 신경 과정의 상호작용을 매개한다
