Selective Inactivation of Leucine-Rich Repeat Kinase 1 and 2 in Dopaminergic Neurons Leads to Age-Dependent Loss of Midbrain Dopaminergic Neurons
Selective inactivation of leucine-rich repeat kinase 1 and 2 (LRRK1 and LRRK2) in dopaminergic neurons leads to age-dependent loss of midbrain dopaminergic neurons, demonstrating the intrinsic importance of LRRK proteins in the survival of dopaminergic neurons.