
Virus-encoded CRISPR-based direct readout screening (VECOS) enables systematic profiling of host dependencies and restrictions across different stages of human cytomegalovirus infection.


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A genetic screen that expresses single guide RNA libraries targeting host genes in&nbsp;the human cytomegalovirus genome&nbsp;enables identification of host factors and provides insights into their roles during the viral replication cycle.

A virally encoded high-resolution screen of cytomegalovirus dependencies - Nature

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Comprehensive Genetic Screen Reveals Critical Host Factors for Human Cytomegalovirus Infection
