
Increased tension at the cell-medium interface, driven by cell contractility, is the key mechanical driver of human embryo compaction, a critical early developmental process.


coremsg

Using micropipette aspiration on donated human embryos, cell surface tensions during compaction were mapped, indicating a role for defective cell contractility in poor quality embryos.

Mechanics of human embryo compaction - Nature

mapping-cell-surface-tensions-and-contractility-mechanisms-during-human-embryo-compaction


Mapping Cell Surface Tensions and Contractility Mechanisms During Human Embryo Compaction
