
Nociceptive sensory neurons, specifically those expressing CGRP, play a crucial role in promoting tissue healing by modulating immune responses and enhancing repair processes.


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Experiments in mouse models show that NaV1.8+&nbsp;nociceptors innervate sites of injury and provide wound repair signals to immune cells by releasing calcitonin gene-related peptide (CGRP).

CGRP sensory neurons promote tissue healing via neutrophils and macrophages - Nature

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The Role of CGRP Sensory Neurons in Tissue Healing
