Interleukin-23 Induces CTLA-4 Expression on Group 3 Innate Lymphoid Cells to Regulate Intestinal Inflammation
Interleukin-23 induces the expression of the immunoregulatory checkpoint molecule CTLA-4 on group 3 innate lymphoid cells (ILC3s), which is essential for restraining the pathological outcomes of IL-23 and maintaining intestinal homeostasis.