深層学習を用いた初期故障検出のための自己符号化器支援特徴量アンサンブルネットワーク

자기부호화기-기반-특징-앙상블-네트워크를-이용한-초기-고장-탐지

gorgeous-generating-unique-character-facial-makeups-from-diverse-inspiration-sources

任意のアイデアから望みのキャラクターの顔メイクアップを作成する

다양한-아이디어로-원하는-캐릭터-페이셜-메이크업-만들기

evaluating-the-capabilities-of-multi-modal-large-language-models-in-generating-diverse-and-controllable-test-inputs-for-visual-deep-learning-systems

多様なモダリティのllmを用いた視覚的深層学習システムのテストのためのベンチマーキング

다양한-멀티모달-대형-언어-모델을-활용한-시각-딥러닝-시스템-테스트를-위한-이미지-변이-벤치마킹


단일 세포 RNA 시퀀싱 데이터를 통해 Syngnathidae의 독특한 특징인 머리 모양, 무치, 피부 갑피, 수컷 임신 등의 발달 유전학적 기반을 규명하였다.


coremsg

Seahorses, pipefishes, and seadragons are fishes from the family Syngnathidae that have evolved extraordinary traits including male pregnancy, elongated snouts, loss of teeth, and dermal bony armor. The developmental genetic and cellular changes that led to the evolution of these traits are largely unknown. Recent syngnathid genomes revealed suggestive gene content differences and provide the opportunity for detailed genetic analyses. We created a single cell RNA sequencing atlas of Gulf pipefish embryos to understand the developmental basis of four traits: derived head shape, toothlessness, dermal armor, and male pregnancy. We completed marker gene analyses, built genetic networks, and examined spatial expression of select genes. We identified osteochondrogenic mesenchymal cells in the elongating face that express regulatory genes bmp4, sfrp1a , and prdm16 . We found no evidence for tooth primordia cells, and we observed re-deployment of osteoblast genetic networks in developing dermal armor.

Finally, we found that epidermal cells expressed nutrient processing and environmental sensing genes, potentially relevant for the brooding environment. The examined pipefish evolutionary innovations are composed of recognizable cell types, suggesting derived features originate from changes within existing gene networks. Future work addressing syngnathid gene networks across multiple stages and species is essential for understanding how their novelties evolved.

Impact Statement The production of a single cell atlas for developing syngnathid fish permits study of their unique traits.

### Competing Interest Statement

The authors have declared no competing interest.

Single Cell RNA Sequencing Provides Clues for the Developmental Genetic Basis of Syngnathidae’s Evolutionary Adaptations

단일-세포-rna-시퀀싱을-통해-syngnathidae의-진화적-적응의-발달-유전학적-기반에-대한-단서-제공


단일 세포 RNA 시퀀싱을 통해 Syngnathidae의 진화적 적응의 발달 유전학적 기반에 대한 단서 제공


title_rewrite

Syngnathidae의 진화적 특성 발달 기반