초기 삼중음성 유방암 환자 중 stromal TIL 수준이 높은 경우 화학요법 없이도 우수한 10년 생존율을 보인다.
Patients with stage I triple-negative breast cancer (TNBC) who have high levels of stromal tumor-infiltrating lymphocytes (TILs) demonstrate excellent 10-year breast cancer-specific survival without chemotherapy, suggesting stromal TILs could be a useful biomarker to optimize treatment decisions in this patient population.
Advancements in targeted therapies, including immune checkpoint inhibitors, antibody-drug conjugates, and drugs targeting replication stress, are transforming the treatment landscape for patients with advanced or recurrent endometrial cancer.
Transvaginal ultrasonography-based endometrial thickness triage strategy has a significant risk of false-negative results for endometrial cancer diagnosis in high-risk Black women.
종양 미세환경의 물리적 특성이 화학요법 내성을 결정하며, 이를 조절함으로써 기존 치료법의 효과를 높일 수 있다.
Targeted surveillance of high-risk individuals can detect pancreatic cancer at an earlier, more treatable stage, leading to significantly improved survival outcomes compared to the general population.
アンドロゲン除去療法によって引き起こされる腫瘍細胞の幹細胞様形質の増加が、腫瘍微小環境のTNFシグナリングを変化させ、免疫抑制を誘導することで、プロステート癌の再発を引き起こす。
CAR-T cell therapies may be directly linked to the development of secondary tumors, particularly those originating from T lymphocytes, according to the European Medicines Agency.
폐암 치료에 있어 항체-약물 접합체(ADC), EGFR 돌연변이, ALK 융합 등 다양한 표적 치료법이 발전하고 있으며, 이를 통해 환자의 생존율 향상과 부작용 감소를 기대할 수 있다.
肺がんの標的療法分野で、抗体薬物複合体(ADC)、EGFR変異、ALK融合遺伝子変異などの新しい治療アプローチが注目されている。これらの治療法は患者の予後を大きく改善する可能性がある。